Voltammetric sensors based on a polyelectrolyte complex and cyclodextrins for the recognition of enantiomers of methionine.
Автор(и)
D. I. Dubrovsky
Bashkir State University, Ufa
R. A. Zilberg
Bashkir State University, Ufa
L. R. Kabirova
Bashkir State University, Ufa
A. I. Habletdinova
Bashkir State University, Ufa
Анотація
As is known, only one of the enantiomers in medicines is biologically active, so the demand for enantiomerically pure preparations is constantly increasing. There are a number of methods for the separation and recognition of enantiomers, such as HPLC, capillary electrophoresis, etc. However, these methods require expensive equipment and considerable time for analysis. An alternative is the voltammetric enantioselective sensors. Methionine is an essential amino acid and component of proteins, a precursor of a number of biologically active compounds that participates in many biochemical processes. The possibility of selective concentration of methionine enantiomers (Met) on a modified glassy carbon electrode (GCE) was studied.
