Gel-like forms of drugs on the basis of solutions of succinamide of chitosan with glycerol.

Анотація

A very serious problem is creation of gels for medical purposes with a given set of properties based on naturally occurring polymers such as chitosan and its derivatives, which have biocompatibility and absence of toxicity. Polymeric gels may be used as transport forms of drugs for wound healing coating and implantable prosthetic devices.

Elastic and plastic (rheological) properties such as viscosity, yield stress, viscous modulus, elasticity modulus, and thixotropy show a number of indicators and quantitative parameters characterizing the processes associated with the production and use of polymer gels. In case of development of polymeric dosage forms, rheological parameters affect the indicators such as ease of use and dosing.