Description of the kinetics of release of amikacin from the polymer matrix.

Анотація

At present the attention of researchers is devoted to the study of polymer systems for controlled release of medicinal substance (MS). For the description of kinetics of release of MS from polymeric systems there is a set of models. Among them it is possible to note the equation of Ritger and Peppas which can be used for the characteristic of release of medicine both from swelling up, and from not swelling up polymeric matrixes. Analysis of the kinetics release of MS from the chitosan films in the conditions of interface of processes of diffusion and dissolution of a polymeric matrix became the purpose of this work.