The study of N-alkyl functionalized indolenine based squaraines as fluorescent probes for proteins detection.

Автор(и)

  • A. S. Syniuhina Taras Shevchenko National University of Kyiv Institute of Molecular Biology and Genetics NASU
  • S. V. Chernii Institute of Molecular Biology and Genetics NASU
  • Yu. L. Slominskii Institute of Organic Chemistry, National Academy of Scinces of Ukraine NASU
  • S. M. Yarmoluk Institute of Molecular Biology and Genetics NASU

Анотація

Squaraine dyes are widely studied as potential fluorescent probes for the labelling and detection of biomolecules, including proteins. Detection of proteins could be useful for chemical and biochemical analyses, biotechnology and immunodiagnostics. Serum albumins are multifunctional proteins present in the blood serum of animals, which bind and transport a variety of ligands. The study of interactions between dye and serum albumins is important for research as a simple diagnostic method for biochemical systems, because albumins concentration could be used as diagnostic parameter.

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Медична та фармацевтична хімія