Oxidation of 8-oxyquinoline by peracids in various organic environments.
Автор(и)
V. V. Kachmaryk
Ivan Franko National University of Lviv
I. M. Nahorniak
Ivan Franko National University of Lviv
Ya. P. Kovalskyi
Ivan Franko National University of Lviv
V. S. Dutka
Ivan Franko National University of Lviv
Анотація
Oxidation of aromatic N-heterocyclic compounds by peroxy acids (PAs) results in the formation of N-oxides and the corresponding carboxylic acid. The reaction rate is affected by the environment in which the oxidation process is conducted. In inert solvents, PA molecules exist in the form of five-membered intramolecular hydrogen bonds. Reaction media capable of intermolecular hydrogen bonding will alter the reactivity of the PA. An 8-oxyquinoline (8OQ) molecule can also form an intramolecular bond between the OH group hydrogen and the nitrogen atom. Conformational analysis of 8OQ and PA molecules was performed and the energies of intramolecular hydrogen bonds were calculated.
