First preparation of iridium-N-XantPhos immobilized catalysts for quinoline hydrogenation

Анотація

Hydrogenation of organic heterocycles is an important process of a modern fine organic and medicinal chemistry, and organometallic phosphine-containing complexes of iridium are efficient homogenous catalysts for such transformation [1]. However, the use of such systems is associated with complicated purification of the products and significant losses of precious metals. Anchoring catalytically active metal coordination compounds on solid supports allows to combine the advantages of both homogenous and heterogenous catalysis. The creation of immobilized catalysts with high activity and stability during repeated use is still a challenging task [2].