Synthesis and biological evaluation of hybrid 1,2,4-triazole derivatives featuring a 1,8-naphthalimide core
Анотація
In this work, we set out to broaden the chemical diversity of 1,2,4-triazoles by integrating them with the compelling heterocyclic scaffold, 1,8-naphthalimide. The naphthalimide unit has recently attracted significant attention for its remarkable photophysical properties, DNAintercalating ability, and demonstrated anticancer and antimicrobial activities [1–4]. By merging these two bioactive frameworks, we aim to develop a novel series of hybrid compounds with potentially synergistic properties.
Посилання
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Dodangeh, Mohammad, Ivo Grabchev, Desislava Staneva, and Kamaladin Gharanjig. “1,8- Naphthalimide Derivatives as Dyes for Textile and Polymeric Materials: A Review.” Fibers and Polymers 22, no. 9 (May 19, 2021): 2368–79. https://doi.org/10.1007/s12221-021-0979-9.
