Synthesis of 2-acetyl-7-amino-3-methyl-5-phenyl-5H-thiazolo[3,2 a] pyrimidine-6-carbonitrile

Анотація

Compounds containing a thiazole ring are of considerable interest in organic synthesis due to their high reactivity and pronounced pharmacological activity. According to the literature, the thiazole heterocycle readily participates in various chemical transformations, including reactions involving oxidation of the nitrogen or sulfur atoms within the ring. However, from a pharmacological standpoint, synthetic approaches that preserve the integrity of the thiazole ring are of greater significance, as compounds obtained in this manner are widely applied as medicinal agents.