Synthesis, antimicrobial activity and admet profiling of 2 substituted thiazolo[3,2-b][1,2,4]triazol-7-ium hexabromotellurates

Автор(и)

  • N. I. Korol Uzhhorod National University, 53/1, Fedytca Str., 88000, Uzhhorod, Ukraine
  • V. V. Pantyo Uzhhorod National University, 53/1, Fedytca Str., 88000, Uzhhorod, Ukraine
  • M. M. Fizer University of Nevada Reno, 1664 N. Virginia Str., Reno, NV, United States
  • M. V. Slivka Uzhhorod National University, 53/1, Fedytca Str., 88000, Uzhhorod, Ukraine

Анотація

The thiazolo[3,2-b][1,2,4]triazol-7-ium hexabromotellurate derivatives 1–3 were synthesized via electrophilic heterocyclization of methallyl thioether precursors using an in situ generated Te(IV) reagent (TeO₂/HBr in CH₃CN) (Fig. 1). This one-step transformation simultaneously constructs the fused heterocyclic core and forms the biologically active TeBr₆²⁻ counterion, ensuring good atom economy and synthetic efficiency.

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Опубліковано

2026-04-14

Номер

2026

Розділ

Органічна хімія