Synthesis of pyrido[1,2-a]pyrimido[4,5-d]pyrimidine derivatives and evaluation of their inhibitory activity against acetylcholinesterase

Автор(и)

  • I. I. Biletskii V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine, Kyiv, Ukraine
  • L. V. Muzychka V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine, Kyiv, Ukraine
  • O. V. Muzychka V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine, Kyiv, Ukraine
  • O. B. Smolii V. P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the NAS of Ukraine, Kyiv, Ukraine

Анотація

Pyrido[1,2-a]pyrimidine derivatives are an important class of bicyclic heterocycles with diverse biological activities. In addition, their use has been reported in the synthesis of tricyclic fused compounds, such as SARS-CoV-2-M Pro, SPOP, and chitinase inhibitors.

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Опубліковано

2026-04-14

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