Synthesis and in silico permeability analysis using the BOILED-Egg model for (E)-1-(2-((2-(1-(2-amino-4-methylthiazol-5-yl) ethylidene)hydrazinyl)methyl)-4-methylthiazol-5-yl)ethanone

Анотація

The synthesis of new thiazole-containing compounds is of significant interest in medicinal chemistry due to their wide range of potential biological activities. Incorporation of a hydrazone fragment into the structure contributes to the expansion of the molecule’s pharmacological profile by enabling the formation of specific interactions with biological targets.