Synthesis of new pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidine-based acetylcholinesterase inhibitors

Анотація

Alzheimer's disease is a prevalent type of dementia characterized by progressive memory loss. Inhibition of acetylcholinesterase is crucial for improving cognitive function in patients with Alzheimer's disease. FDA-approved drugs, such as donepezil, that inhibit acetylcholinesterase are used for the symptomatic treatment of Alzheimer's disease.