Knoevenagel reaction catalyzed by iron(III) 1,3,5-benzenetricarboxylate in flow

Authors

  • Enamine Ltd, Kyiv, L. V. Pisarzhevskii Institute of Physical Chemistry of the National Academy of Sciences of Ukraine
  • Enamine Ltd, Kyiv, National Taras Shevchenko University of Kyiv
  • L. V. Pisarzhevskii Institute of Physical Chemistry of the National Academy of Sciences of Ukraine

Abstract

C-C coupling reactions play important role in fine and industrial organic synthesis. Knoevenagel reaction – interaction of aldehydes or ketones with active methylene compounds – is one of the ways to form C-C bond. Development of the efficient heterogeneous catalysts for the Knoevenagel reaction is urgent task [1].

References

K. van Beurden, S. de Koning, D. Molendijk, J. van Schijndel, Green Chem. Let. and Rev., 2020, 13:4, 349–364.

S. A. Sotnik, S. V. Kolotilov, M. A. Kiskin, Zh. V. Dobrokhotova, K. S. Gavrilenko, V. M. Novotortsev, I. L. Eremenko, V. K. Imshennik, Yu. V. Maksimov, V. V. Pavlishchuk, Russ. Chem. Bull., 2014, 63, 862–869.

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Published

2021-05-13

Issue

2021

Section

Physical Chemistry