Synthesis of pyrido-pyrimidine and imidazo-pyridine derivatives

Abstract

Nitrogen containing heterocycles are important molecules in organic chemistry and their structures are present in many natural products and play important role in medicinal chemistry. Pyrido[1,2-a]pyrimidine derivatives shows pharmacological activities such as antidepressant, gastrointestinal protective, neurotropic, stress-protecting and anticancer properties. This structure is also a component of some of the marketed drugs, like pemirolast, pirenperone and barmastine.