Synthesis of chalcones based on 1-(2-amino-4-methylthiazol-5- yl)ethan-1-one

Abstract

Despite the large-scale synthesis of drugs, the fight against infectious diseases is still not at the desired level.The reason for this is the large number and variety of pathogenic microorganisms that are resistant to existing drugs. Although the synthesized drugs have the necessary effect on existing microorganisms and weaken their resistance, some microorganisms develop adaptations to these drugs.For this reason, the long-term use of a number of drugs may be ineffective.For this reason, the preparation of drugs with properties that can have a longterm effect on microorganisms is very important.