In silico evaluation of physicochemical properties and ADME profile of the (Е)-1-(2-((2-(1-(2-amino-4-methylthiazol-5-yl) ethylidene)hydrazinyl)methyl)-4-methylthiazol-5-yl)ethanone

Authors

  • F. M. Abdullayeva Azerbaijan State Oil and Industry University, Baku, Azerbaijan, Ministry of Science and Education of the Republic of Azerbaijan, Institute of Petrochemical Processes named after academician Y. G. Mamedaliyev
  • A. S. Safarova Baku State University, Baku, Azerbaijan
  • E. Z. Huseyinov Baku State University, Baku, Azerbaijan
  • F. N. Naghiyev Baku State University, Baku, Azerbaijan

Abstract

Modern approaches to drug design rely heavily on in silico methods that allow early-stage evaluation of the physicochemical properties and pharmacokinetic parameters of potential bioac-tive compounds. Prediction of absorption, distribution, metabolism, and excretion (ADME) para-meters plays a key role in identifying promising candidates and reducing the risk of failure at later stages of research.

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Published

2026-04-14

Issue

2026

Section

Organic Chemistry