Merocyanines as fluorescent probes for the detection in microscopy

Автор(и)

  • S.V. Chernii Institute of Molecular Biology and Genetics NASU
  • A.T. Syniugina Institute of Molecular Biology and Genetics NASU
  • A.R. Syniugin Institute of Molecular Biology and Genetics NASU
  • M.Yu. Losytskyy Institute of Molecular Biology and Genetics NASU
  • Yu.L. Slominskii Institute of Organic Chemistry NASU
  • S.M. Yarmoluk Institute of Molecular Biology and Genetics NASU
  • A.A. Mokhir Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany
  • V.B. Kovalska Institute of Molecular Biology and Genetics NASU, Scientific Services Company Otava Ltd

Анотація

Nowadays, the study of the drug distribution in cells is becoming an increasingly actual method of biomedical research. Far-red fluorescent probes are highly applicable due to certain advantages such as minimum photo-damaging of biological samples, high tissue penetration and allow imaging with minimal to no autofluorescence. The aim of the research was to study the novel series of far-red merocyanine dyes containing modified polymethine bridges by fluorescence microscopy.

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Опубліковано

2021-04-19

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Розділ

Медична та фармацевтична хімія