New method for assessment of hydrogenation catalysts activity by estimation of imidazo[1,5-a]pyridines reduction time using UV-spectroscopy.
Authors
M. O. Ivanytsya
L. V. Pisarzhevskii Institute of Physical Chemistry of the NAS of Ukraine
Enamine Ltd
A. S. Lytvynenko
L. V. Pisarzhevskii Institute of Physical Chemistry of the NAS of Ukraine
S. A. Sotnik
L. V. Pisarzhevskii Institute of Physical Chemistry of the NAS of Ukraine
Enamine Ltd
V. V. Buryanov
Enamine Ltd
D. O. Tverdiy
Institute of Molecular Biology and Genetics NAS of Ukraine
S. V. Ryabukhin
Enamine Ltd
D. M. Volochnyuk
Enamine Ltd
Institute of Organic Chemistry of the NAS of Ukraine
S. V. Kolotilov
L. V. Pisarzhevskii Institute of Physical Chemistry of the NAS of Ukraine
Abstract
Hydrogenation catalysts are widely used in modern fine organic synthesis for preparation of active pharmaceutical ingredients (API), compounds for agrochemistry, etc. Evaluation of such catalysts' activity is important task, because the properties of such systems strongly depend on their preparation method. Development of simple method for catalysts activity assessment is required for experiment planning as well as catalysts quality control.
